Mtengo wochulukira 100% Pure Forsythiae Fructus mafuta Relax Aromatherapy Eucalyptus globulus

Mtengo wochuluka 100% Pure Forsythiae Fructus oil Relax Aromatherapy Eucalyptus globulus Chithunzi Chowonetsedwa

Kufotokozera mwachidule:

Forsythia amatsutsana(Thunb.) Vahl. (Family Oleaceae) ndi chitsamba chokongoletsera, zipatso zake zimagwiritsidwa ntchito ngati TCM yodziwika bwino "Forsythiae Fructus" (FF) (连翘in Chinese). Makhalidwe a TCM a FF amafotokozedwa mwachidule ngati owawa mu kukoma, ndi kuzizira pang'ono ndi mapapu, mtima kapena matumbo a meridian meridian (Pharmacopoeia Commission of PRC, 2015), makhalidwe amenewo akufanana ndi mawonekedwe a anti-inflammatory TCM, malinga ndi Chen. ndi Zhang (2014). Mu zitsamba za Shennong, FF idagwiritsidwa ntchito pochiza pyrexia, kutupa, gonorrhea, carbuncle ndi erysipelas (Cho et al., 2011). Mitundu iwiri ya FF ilipo, zipatso zakupsa zobiriwira zotchedwa "Qingqiao" ndi zachikasu zakupsa zomwe zimatchedwa "Laoqiao". Onsewa amagwira ntchito ngati magwero ovomerezeka a FF, komabe, Qingqiao imagwiritsidwa ntchito pafupipafupi m'mawu a TCM (Jia et al., 2015). Madera akuluakulu omwe amapanga FF ndi Hebei, Shaanxi, Shanxi, Shandong, Anhui, Henan, Hubei, Jiangsu (olimidwa) ndi zigawo za Sichuan (Editorial Board of Flora of China, 1978).

Mu kope la 2015 Chinese Pharmacopoeia, mankhwala 114 aku China omwe ali ndi FF alembedwa, monga Shuanghuanglian oral solution, Yinqiao Jiedu mapiritsi, Niuhuang Shangqing mapiritsi, ndi zina (Pharmacopoeia Commission of PRC, 2015). Kafukufuku wamakono akuwonetsa anti-yotupa (Kim et al., 2003), antioxidant (CC Chen et al., 1999), antibacterial (Han et al., 2012), anti-cancer (Hu et al., 2007), anti -virus (Ko et al., 2005), anti-allergy (Hao et al., 2010), neuroprotective (S. Zhang et al., 2015) zotsatira,ndi zina.Ngakhale kuti chipatso chokhacho chimagwiritsidwa ntchito ngati TCM, maphunziro ena adanenanso za phytochemistry ndi pharmacological zotsatira za masamba (Ge et al., 2015, Zhang et al., 2015), maluwa (Takizawa et al., 1981) ndi mbewu (Zhang et al. ., 2002).F. suspensa. Chifukwa chake, tsopano tikupereka chiwongolero chatsatanetsatane cha zomwe zilipo zaF. suspensa, kuphatikizapo ntchito zachikhalidwe, botani, phytochemistry, pharmacology, toxicity, pharmacokinetics ndi kulamulira khalidwe. Komanso, njira zomwe zingatheke mtsogolo mwa kafukufuku zimakambidwa.

Zigawo zagawo

Ntchito zachikhalidwe

M'malemba akale achi China azitsamba, FF imalembedwa kuti ndi yothandiza pochiza rat fistula, scrofula, carbuncle, zilonda zowopsa, chotupa cha ndulu, kutentha ndi poizoni (zitsamba za Shennong, Bencao Chongyuan, Bencao Zhengyi, Zhenglei Bencao). Malinga ndi akatswiri ambiri akale, therere lachipatalali ndi lothandiza kwambiri pochotsa kutentha kwa mtima ndi kutulutsa chinyontho - kutentha kwa ndulu ndi m'mimba. Ndiwochiritsira pochiza stranguria, edema, qi stagnancy ndi stasis yamagazi.

Zomera

F. suspensa(Weeping Forsythia) ndi chitsamba chokongola chochokera ku China, chomwe chimakula mpaka kutalika kwa 3 m (mkuyu 1). Ili ndi ma internodes omwe ali ndi nthambi zotambalala kapena zopindika zomwe zimakhala zachikasu-bulauni kapena zotuwa. Masamba amakhala osavuta, koma nthawi zina 3-foliolate. Masamba ndi ovate, ovate kwambiri, kapena elliptic-ovate ndi 2-10 × 1.5-5 cm2 mu kukula kwake ndi ozungulira kuti cuneate maziko ndi pachimake pamwamba. Mbali zonse za masamba ndi zobiriwira, glabrous ndi sharply kapena coarsely

Phytochemistry

Masiku ano, mankhwala 237 apezekaF. suspensa, kuphatikizapo 46 lignans (1-46), 31 phenylethanoid glycosides (47-77), 11 flavonoids (78-88), 80 terpenoids (89-168), 20 cyclohexylethanol zotumphukira (169-188), alkaloids zisanu ndi chimodzi ), ma steroidal anayi (195-198) ndi 39 mankhwala ena (199-237). Pakati pawo, zigawo ziwiri (21-22) zinali olekanitsidwa ndi maluwa aF. suspensa, Zigawo za 19 (94-100, 107-111, 115-117, 198, 233-235) zidalekanitsidwa ndi masamba aF. suspensa, zigawo zinayi

Zotsutsana ndi kutupa

Zochita zotsutsana ndi zotupa za FF zimathandizira kuyeretsa kwake kutentha (Guo et al., 2015). Kutupa ndikuyankhidwa kwakuthupi pakukondoweza kwa matenda, matupi awo sagwirizana, kapena mankhwala (Lee et al., 2011). Zimayambitsa matenda aakulu, monga matenda a khungu, chifuwa, ndi khansa,ndi zina.FF ndi imodzi mwa TCM yomwe ili ndi mphamvu zotsutsana ndi kutupa, imagwiritsidwa ntchito kwambiri pa kutupa kosatha komanso koopsa. Zochita zolimbana ndi kutupa za FF zidakhala pamwamba zisanu pakati pa 81 zoyesedwa TCM (70% ethanol

Poizoni

Mpaka pano, palibe lipoti la poizoni wa FF. Mlingo watsiku ndi tsiku wa FF uyenera kukhala 6-15 g (Pharmacopoeia Commission of PRC, 2015). Zogwirizana ndi malipoti anasonyeza kuti palibe pachimake kawopsedwe madzi kapena Mowa Tingafinye masamba aF. suspensamu mbewa, ngakhale pa mlingo wa tsiku ndi tsiku wa 61.60 g / kg (Ai et al., 2011, Hou et al., 2016, Li et al., 2013). Han et al. (2017) adanenanso kuti palibe poizoni wa phillyrin (kuchokera masamba aF. suspensa)mu mbewa za NIH (18.1 g/kg/tsiku, po, kwa masiku 14) kapena ayi

Pharmacokinetics

Li et al. adazindikira magawo asanu ndi anayi a metabolites a phillyrin m'masampula amkodzo a makoswe ndikuwonetsa njira zake zama metabolic mu makoswe. Phillyrin poyambilira adapangidwa ndi hydrolyzed kukhala phillygenin kenako adasinthidwa kukhala ma metabolites ena makamaka kudzera mu methylation, demethylation, dehydroxylation ndi njira zotsegulira mphete (Li et al., 2014c). H. Wang ndi al. (2016) adazindikira 34 gawo I ndi gawo II metabolites a phillyrin ndipo adawonetsa kuti hydrolysis, oxidation ndi sulfation zinali zazikulu.

Kuwongolera khalidwe

Kuwongolera mtundu wa FF, Chinese Pharmacopoeia ikuwonetsa chizindikiritso cha morphological, microscopic ndi TLC kuphatikiza kutsimikiza kwa HPLC. Zitsanzo za FF zoyenerera ziyenera kukhala ndi phillyrin yoposa 0.150% (Pharmacopoeia Commission of PRC, 2015).

Komabe, chikhomo chimodzi chokha, phillyrin, chikuwoneka chosakwanira kuwunika mtundu wa FF. Posachedwapa, magawo osiyanasiyana a bioactive mu FF adawunikidwa ndi ma chromatography, electrophoresis, MS ndi njira za NMR, monga

Mapeto ndi malingaliro amtsogolo

Ndemanga yomwe ilipo ikufotokoza mwachidule zambiri zokhudzana ndi kugwiritsidwa ntchito kwachikhalidwe, botani, phytochemistry, zotsatira za mankhwala, kawopsedwe, pharmacokinetics ndi kuwongolera khalidwe laF. suspensa. M'malemba akale achi China azitsamba komanso Chinese Pharmacopoeia, FF imagwiritsidwa ntchito kwambiri pochotsa kutentha komanso kuchotseratu poizoni. Mpaka pano, mankhwala opitilira 230 adasiyanitsidwa ndikuzindikiridwa kuchokera ku zitsamba izi. Pakati pawo, lignans ndi phenylethanoid glycosides amaonedwa ngati khalidwe ndi bioactive

Zithunzi za TCM

Yin: "Yin" ndi imodzi mwa mphamvu ziwiri zotsutsana za chilengedwe, malinga ndi chilengedwe chakale cha ku China. "Yin" amadziwika kuti ndi wodekha, wofewa, wololera, wofalikira, wozizira, wonyowa kapena wabata, ndipo amagwirizanitsidwa ndi madzi, dziko lapansi, mwezi, ukazi ndi usiku.

Qi: M'mawu oti acupuncture, "qi" ndi "mphamvu ya moyo". Ndiwo gwero la mayendedwe onse m'thupi, chitetezo pakuwukiridwa kwa thupi, gwero lazochita zonse za metabolic, zimapatsa kusungidwa kwa minofu.

Kuyamikira

Ntchitoyi idathandizidwa ndi Beijing Joint Project of Science Research ndi maphunziro apamwamba-Kafukufuku waukadaulo wofunikira komanso kugwiritsa ntchito kuwunika kwachitetezo chamankhwala akupha aku China potengera kapangidwe kake ndi mawonekedwe a zebrafish.

Mtengo wa FOB:US $0.5 - 9,999 / Chigawo

Kuchuluka kwa Min.Order:100 zidutswa / zidutswa

Kupereka Mphamvu:10000 Chidutswa/Zidutswa pamwezi

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Kufunika kwa Ethnopharmacological

Forsythiae Fructus (wotchedwa Lianqiao m'Chitchaina), chipatso chaForsythia amatsutsana(Thunb.) Vahl, amagwiritsidwa ntchito ngati mankhwala wamba ku China, Japan ndi Korea. Amagwiritsidwa ntchito pochiza pyrexia, kutupa,chinzonono,carbunclendierysipelas. Kutengera nthawi yokolola yosiyana, Forsythiae Fructus imatha kugawidwa m'mitundu iwiri, yomwe ndi Qingqiao ndi Laoqiao. Zipatso zobiriwira zomwe zimayamba kupsa zimatengedwa ngati Qingqiao, pomwe zipatso zachikasu zomwe zakhwima zimatengedwa ngati Laoqiao. Zonsezi zimagwiritsidwa ntchito pazachipatala. Ndemanga iyi ikufuna kupereka chidule cha ndondomeko yaF. suspensa(Forsythia amatsutsana(Thunb.) Vahl) ndi kuwulula kugwirizana pakati pa ntchito zachikhalidwe ndintchito za pharmacologicalkuti apereke chilimbikitso cha kafukufuku wamtsogolo.

Zida ndi njira

Zonse zogwirizana zokhudzaF. suspensaidafufuzidwa ndi Scifinder ndipo idapezedwa kuchokera ku nkhokwe zasayansi kuphatikiza Springer, Science Direct, Wiley, Pubmed ndi China Knowledge Resource Integrated (CNKI). Zolemba zakumaloko komanso mabuku adafufuzidwanso.

Zotsatira

Malinga ndi zolemba zakale zaku China zaku China Pharmacopoeia, Forsythiae Fructus nthawi zambiri amawonetsa kutentha komanso kuchotseratu poizoni.Mtengo wa TCMmalangizo. Mu kafukufuku wamakono, zoposa 230 mankhwala analekanitsidwa ndi kuzindikiridwaF. suspensa. 211 Mwa iwo anali olekanitsidwa ndi zipatso.Lignansndi phenylethanoidglycosidesamaonedwa ngati mawonekedwe ndi yogwira zigawo za therere, monga forsythiaside, phillyrin,rutinndi phillygenin. Amawonetsa anti-yotupa, antioxidant, antibacterial, anti-virus, anti-cancer ndi anti-allergenic zotsatira,ndi zina.Pakadali pano, palibe lipoti lokhudza kawopsedwe ka Forsythiae Fructus, ngakhale kawopsedwe kakang'ono ka forsythiaside kamafotokozedwa m'mabuku akomweko. Poyerekeza ndi Laoqiao, Qingqiao ili ndi milingo yayikulu ya forsythiaside, forsythoside C, cornoside,rutin, philirin,asidi gallicndichlorogenic acidndi milingo yotsika ya rengyol,β- glucose ndi S-suspensasidemethyl ether.

Mapeto

Zochita zochotsa kutentha kwa Forsythiae Fructus zimatengera anti-inflammatory and antioxidant properties of lignans ndi phenylethanoid.glycosides. Kuchotsa poizoni kumabwera chifukwa cha antibacterial, antiviral ndi anti-cancer zochita za Forsythiae Fructus. Ndipo machitidwe achi China achi China (TCM) a Forsythiae Fructus (kununkhira kowawa, chikhalidwe chozizira pang'ono ndi meridian ya m'mapapo) adathandizira zotsatira zake zotsutsana ndi kutupa. Komanso, odana ndi yotupa ndi zodabwitsaantioxidant mphamvuForsythiae Fructus imathandizira pakulimbana ndi khansa komansoneuroprotectiventchito. Kuchuluka kwa ma lignans ndi phenylethanoid glycosides ku Qingqiao kuposa Laoqiao kungafotokozere luso la antioxidant la Qingqiao komanso kugwiritsa ntchito Qingqiao pafupipafupi.Mtengo wa TCMmalangizo. Zofufuza zamtsogolo, zambirimu vivozoyesera ndi maphunziro azachipatala akulimbikitsidwa kuti afotokozerenso kugwirizana pakati pa kugwiritsidwa ntchito kwachikhalidwe ndi ntchito zamakono. Ponena za Qingqiao ndi Laoqiao, atsala kuti azisiyanitsidwa ndi njira zonse zowongolera khalidwe, ndipo mapangidwe a mankhwala ndi zotsatira zachipatala pakati pawo ziyenera kufananizidwa.