Mafuta onunkhira amafuta onunkhira onunkhira onunkhira a makandulo ndi sopo opanga mafuta ophatikizira mafuta ofunikira atsopano opangira mabango.
Zida ndi njira
Tidagwiritsa ntchito zitsanzo zama cell kuti tifufuze zotsutsana ndi zotupa komanso antiviral za SS yaiwisi ndi SSC. Nthawi yotaya magazi ya chitsanzo cha magazi mchira ndinthawi ya clottingNjira ya capillary mu mbewa idagwiritsidwa ntchito kufananiza zinthu za hemostasis za SS yaiwisi yaiwisi ndi SSC. Mafotokozedwe amankhwala a SS ndi SSC adafanizidwa pogwiritsa ntchito njira yophatikizira gas chromatography-mass spectrometry (GC-MS) ndi kusanthula kwamadzi amadzimadzi / quadrupole-time-of-flight mass spectrometry (HPLC/Q-TOF-MS).
Zotsatira
Zotsutsana ndi zotupa za SSC zinali zochepa kwambiri kuposa za SS yaiwisi. SS yaiwisi yaiwisi ndi SSC inaletsa bwino matenda a tizilombo toyambitsa matenda motsatira mlingo, ndi IC50 miyeso ya 96.30 ndi 9.73 μg / mL ndi selectivity index (SI) ya > 1.56 ndi 7.78, motsatira. Chochititsa chidwi, SSC idawonetsa mphamvu zambirintchito zoletsa ma viruskuposa SS yaiwisi. Kuwongolera kwa intragastric kwa SS yaiwisi ndi SSC kwa mbewa kunawonetsa kutihemostaticZotsatira za SSC zinali zamphamvu kuposa za SS yaiwisi. Poyerekeza ma profiles osasunthika a SSC, tidapeza kuti zigawo makumi awiri mphambu zisanu ndi zinayi zidasowa ndipo zigawo zatsopano makumi asanu ndi zinayi zidapangidwa pomwe zomwe zili m'magulu ena asanu zidachepa ndipo zigawo zina zitatu zidakula. Kuphatikiza apo, mawonekedwe osasinthika amafuta a SS yaiwisi ndi SSC adasiyana, okhala ndi nsonga zotsika makumi atatu ndi ziwiri komanso nsonga zisanu ndi ziwiri zapamwamba mu SSC kuposa mu SS.
Mapeto
Kafukufuku wathu adawonetsa kuti SS yaiwisi ndi SSC zimathandizira mchitidwe wachikhalidwe pazogwiritsa ntchito mankhwala awiriwa kupatula SS yaiwisi yomwe imagwiritsidwa ntchito pochiza matenda a virus. Ndizovuta kwambiri kupanga ma SSC okhala ndi zochitika zachikhalidwe za hemostatic komanso antiviral mutatha kukonza mwachangu. Kuphatikiza apo, zinthu zosasinthika komanso zosasinthika zamankhwala a SS yaiwisi zidasintha kwambiri pakukonza. Kafukufuku wina akuyenera kufufuza ngati kusintha kwa zigawo za mankhwala kumagwirizana ndi cholinga chokonzekera.