Koyera zachilengedwe organic magnolia zofunika mafuta flos magnoliae mafuta mafuta onunkhira
Magnoliae Flos ndi mankhwala omwe amagwiritsidwa ntchito kwambiri ku Asia. Amagwiritsidwa ntchito pochiza sinusitis, kutsekeka kwa m'mphuno, ndi khungu la hypersensitive. Chifukwa Magonlia Flos amafotokozedwa ngati chinthu chonunkhira m'malemba akale achi China, tidaganiza kuti mafuta ake ofunikira atha kugwiritsidwa ntchito pochiza matenda a chitetezo chamthupi. Ma cell a dendritic (DCs), omwe amawonedwa ngati chandamale chachikulu cha ma immunomodulators kuti athe kuwongolera mayankho a chitetezo chamthupi, amatenga gawo lofunikira pakuyankha kwa chitetezo chamthupi. Mu phunziro ili, Magnoliae Flos mafuta ofunikira (MFEO) adachepetsa kupanga ma cytokines TNF-α" role = "presentation" style="box-size: border-box; chiwonetsero: mkati; kutalika kwa mzere: zachilendo; kusiyana kwa mawu: mwachibadwa; kusefukira-kukuta: zachilendo; malo oyera: nowrap; zoyandama: palibe; njira: ltr; m'lifupi mwake: palibe; utali wautali: palibe; m'lifupi mwake: 0px; min-utali: 0px; malire: 0px; kukwera: 0px; malire: 0px; udindo: wachibale;”>α
, IL-6, ndi IL-12p70 mu lipopolysaccharide (LPS) -zolimbikitsa DCs. Idaponderezanso zolembera za MHC II, CD80, ndi CD86 mu LPS-stimulated DCs. Zitsanzo za zinyama zimasonyeza kuti 2,4-Dinitro-1-fluorobenzene (DNFB) yomwe imayambitsa kukhudzana ndi hypersensitivity kuyankha inali yoletsedwa kutsatira chithandizo ndi MFEO. Kuonjezera apo, MFEO inaletsa kulowetsa kwa maselo a T m'makutu a mbewa za DNFB. Kuti mufufuze mankhwala ake a bioactive, zigawo za MFEO zinawunikidwa pogwiritsa ntchito gas chromatography (GC) ndi GC-mass spectrometry. Zotsatira zinawulula kuti mankhwala akuluakulu mu MFEO ndi camphor ndi 1,8-cineole. Ma bioassays owonjezera a DC adatsimikizira kuti mankhwalawa amapondereza kwambiri kupanga ma cytokine mu ma DC opangidwa ndi LPS. Chifukwa chake, tidawonetsa kuti MFEO imawonetsa immunosuppressive yonsemu vivondimu vitro, ndi camphor ndi 1,8-cineole zikhoza kukhala zigawo zikuluzikulu zomwe zimayambitsa mphamvu zake zowononga chitetezo cha mthupi. Zomwe zapezazi zikuwonetsa kuti MFEO ili ndi kuthekera kopangidwa ngati njira yatsopano yothanirana ndi matenda ochulukirapo.