Mafuta a Ylang-ylang

Ylang-ylangmafuta ofunikira (YEO), otengedwa ku maluwa a mtengo wotenthaKanangaodorataHook. f. & Thomson (FamilyAnnonaceae), yakhala ikugwiritsidwa ntchito kwambiri muzamankhwala ndi ntchito zambiri, kuphatikizapo nkhawa ndi kusintha kwa neuronal states. Ululu wa Neuropathic ndi vuto lopweteka kwambiri lomwe limakhala ndi zovuta zambiri, monga nkhawa, kukhumudwa, ndi zovuta zina zamalingaliro, zomwe zimakhudza kwambiri moyo wa wodwalayo. Mankhwala omwe alipo panopa omwe amagwiritsidwa ntchito poyang'anira ululu wa neuropathic ndi osakwanira chifukwa chosagwira ntchito bwino komanso kulekerera, kuwonetsa kufunikira kwamankhwala kwa pharmacotherapy yabwino. Kafukufuku wambiri wachipatala wasonyeza kuti kutikita minofu kapena kupuma ndi mafuta ofunikira osankhidwa kumachepetsa zizindikiro zokhudzana ndi ululu ndi nkhawa.

Cholinga cha phunziroli chinali kufufuza za analgesic propertiesYEOndi mphamvu yake yochepetsera kusintha kwamalingaliro kokhudzana ndi neuropathy.

Ma analgesic properties adayesedwa mu njira yopulumutsira mitsempha pogwiritsa ntchito mbewa zamphongo. Anxiolytic, antidepressant, ndi locomotor katundu adawunikidwanso pogwiritsa ntchito mayeso amakhalidwe. Pomaliza, makina a YEO adafufuzidwa mu msana ndi hippocampus ya mbewa za neuropathic.

Oral kasamalidwe kaYEO(30 mg / kg) inachepetsa ululu wa SNI-induced neuropathic ndikutsitsimutsa zizindikiro za nkhawa zokhudzana ndi ululu zomwe zinkawoneka masiku 28 pambuyo pa opaleshoni.YEOadachepetsa mawu a MAPKs, NOS2, p-p65, zolembera za neuroinflammation, ndikulimbikitsa kukhazikika pamilingo ya neurotrophin.

YEOKuchepetsa kupweteka kwa neuropathic komanso kumachepetsa nkhawa yokhudzana ndi ululu, zomwe zimayimira munthu wokonda kuyang'anira zowawa za neuropathic komanso zovuta zokhudzana ndi ululu.